Job Details

Senior Bioanalytical Scientist

Company name
Monsanto Company

Saint Louis, MO

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Senior Bioanalytical Scientist','01N2J','!*!

Are you looking for a technology-focused company where the research and atmosphere inspire you to do your very best, and support your career? If so, then be empowered to take charge of your future at Monsanto. Our mission is to help farmers around the world growing food more sustainably - from seed to software, to fiber and fuel, we’re developing tools to help growers protect natural resources while providing nourishment to the world. In the face of a changing climate and other environmental challenges, we’re providing solutions to ensure that our agricultural system continues to suit the needs of everyone. At Monsanto, over 20,000 employees in 67 countries are using a variety of skills, training, and expertise to help modern agriculture grow and conserve; Together we feed the world and protect the planet!We are seeking a highly motivated Senior Bioanalytical Scientist with mass spectrometry-based proteomics experience to join our Protein group in Biotechnology. This person will be a vital supporter of expanding proteomics capabilities and align with Protein Engineers, Structural Biologists, Biophysicists and Genomic Data Scientists to enable a deeper understanding of our molecular targets, and ultimately support engineering of novel protein variants with improved target properties relevant to the project teams. Our team supports the Biotech product development pipeline and product stewardship by providing biophysical and functional characterization of proteins, development of new protein functional assays, biochemical characterization of insects and insect resistance mechanisms, and mechanism-of-action studies of insecticidal and other lead pipeline proteins. The team is also responsible for insect proteomics as well as discovery and verification of protein identity through mass spectrometry. This position will be assay development-centric and we are looking for a highly motivated candidate who has a strong academic background in the biological sciences.Responsibilities include:• Identify and implement current and emerging MS approaches internally and/or via industry/academic partnerships• Design, develop and implement MS experiments and communicate results effectively to collaborators to support protein engineering of new insecticidal traits• Operate and maintain different types of LC-MS/MS instruments• Collaborate closely with protein engineers, structural biologists, biophysicists and project leads • Align with data scientists and enterprise IT architects to develop tools for rapid proteomics data processing, visualization and timely decisions','!*!Required Education and Skills/Experience:• Minimum of a Ph.D. in Biochemistry, Chemistry, or a related discipline – OR – Minimum of Master’s degree with a minimum of five or more years of experience• Minimum of three or more years of hands-on research experience with applied mass spectrometry-based techniques• Prior experience in proteomics• Prior peer-reviewed publication in the field• Hands-on experience with the operation and maintenance of LC-MS/MS instruments• Excellent experimental design, communication, organizational skills and great work ethic• Capable of learning new concepts and techniques at a rapid rateDesired Education and Skills/Experience:• Strong background in HDX and peptide mapping technologies • Knowledge of automated liquid handling applied to protein mass spectrometry work-flows• Ability to characterize covalent modifications of proteins by mass spectrometry• Knowledge of software commonly used in mass spectrometric analyses• Strong background in performing quantitative mass spectrometry based strategies including isotopic labeling, isobaric tagging, SILAC, and/or label-free analysis (DIA, PRM/SRM)• Prior experience with product development• Academic background in Biology and/or Biochemistry • Experience with membrane proteins• Familiarity with biophysical techniques such as SPR, ITC, DLS, and/or TSA• Familiarity with structural biology methods such as X-ray crystallography, NMR and/or ER • Proficient in scripting languagesWho is Monsanto? Monsanto is an agriculture company with more than 20,000 employees focused on making a balanced meal accessible to everyone. We work to help farmers produce food in a more sustainable way. We think about how our food is grown so farmers have the tools they need to have better harvests.We believe that bringing diverse perspectives together is the most effective way to develop creative solutions to some of the world’s biggest challenges. Career opportunities at Monsanto range from farming, plant breeding, chemistry and engineering to marketing, environmental science, IT and many other areas. We’re always looking for exceptional professionals interested in developing a strong career while collaborating to develop solutions for sustainable agriculture. Sound like a job for you?Why work with us?• Life at Monsanto means collaborating with dedicated professionals in a stimulating environment• Our people demonstrate our winning culture through positive and meaningful relationships• You will work with market leading brand products in a global organization• We provide competitive salaries, excellent benefits, and some of the best career development opportunities in the industry• Monsanto is named Great Place to Work in many countries around the worldJoin our global team where your contribution will make a real difference!','Research & Development','North America-USA-Missouri-St. Louis','','US Biotech-Trait Design and Science_51013268','Full-time','Senior Bioanalytical Scientist

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Monsanto Company
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Company Profile
At the heart of Monsanto is a very clear and principled code of conduct – one we expect all employees, contractors and management to live by every day. We operate under a genuine value system—our pledge—that demonstrates integrity, respect, ethical behavior, perspective and honesty as a foundation for everything we do.

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